Tim Fitzgerald, MFA, CMI

This molecular illustration shows the membrane-bound proteins involved in the uptake of a virus particle into the cell. Reading from left to right, the arrows show how the proteins pass the virus down the line until it reaches the final protein that will trigger the endocytosis.

This scientific illustration inset (from a larger poster) shows the anatomy of a rotavirus particle. The different capsids that surround the RNA strands are isolated and positioned within a flat, gray virus shape to show their relevant size and position within the complete virus.

The original sketch for this infographic was made at a ‘SciArt Meetup’ event at the Florida Museum of Natural History (color and graphical details added afterwards). The graphics on the left include a breakdown of the time period and geographical location of the ancient animal’s existence.

This is an image of conotoxin and an inset of how it affects a voltage-gated calcium channel (VGCC). Conotoxin is a peptide toxin created by a tropical marine snail ( Conus victoriae ). Aside from VGCCs, the toxin also targets voltage-gated sodium channels, voltage-gated potassium channels, and nicotinic acetylcholine receptors. Conotoxins are being explored as an option for pain-relief therapy.

This image, sized for a science journal, shows one effect of chlorpyrifos on the human body, particularly in the nervous system. In the ‘normal’ scenario, the enzyme acetylcholinesterase (or cholinesterase) breaks down the neurotransmitter, acetylcholine. In the clinical scenario, the pesticide inhibits the enzyme from working properly, thus leading to an accumulation of acetylcholine. The build-up can cause over-stimulation of nerves, muscles, and glands.

Wobbler Disease -  Cervical spondylomyelopathy (CSM) This infographic gives an overview of this particular company’s treatment for ‘wobbler disease’. The MRIs, supplied by the company, were colorized to highlight the symptoms of the disease and progression of treatment. Comparisons of the healthy and unhealthy postures of a dog suffering from this syndrome are included in this graphic.

This illustration was part of a proposal for a pharmaceutical company’s presentation. The illustration shows molecules in the extracellular space hovering over proteins that are embedded in a lipid bilayer. There are visuals underneath the proteins to symbolize the actions that occur downstream when the molecules bind to their receptors.

This illustration is a colored interpretation of the Circle of Willis found in angiogram images (small branches excluded). The layout includes an orientation of the scan level, as well as orthographic views of the arteries in a complete brain for context.

This illustration is a colored interpretation of a disc herniation and osteophytes in a female patient's neck. The layout includes an orientation image to give viewers familiarity with the level of the scan.

This infographic compares the molecular similarities between smoking addiction and quit-smoking medications. In short, they both cause the release of dopamine (a neurotransmitter); the effects on health come down to how the body obtains the initial molecules to start the release.

This infographic shows different anatomical structures present in the original MRI image. Using a computer program, different layers of tissue were removed to reveal other ones; that is how different illustrations of different anatomical structures were made all from the same view.

This infographic compares the normal condition of neuron-muscle communication, and the clinical condition of myasthenia gravis. The images show the molecular and cellular components involved with each circumstance.